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Purification of micronuclei from cultured cells by flow cytometry
Micronuclei are aberrant nuclear compartments that form when chromosomes or chromosome fragments fail to incorporate into a primary nucleus during mitotic exit. Ruptures at the micronuclear envelope are associated with DNA damage and activation of immune sensing pathways. To gain insights into these...
Autores principales: | Toufektchan, Eléonore, Maciejowski, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982749/ https://www.ncbi.nlm.nih.gov/pubmed/33778777 http://dx.doi.org/10.1016/j.xpro.2021.100378 |
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