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Value of Adaptive Trials and Surrogate Endpoints for Clinical Decision-Making in Rare Cancers

Despite high-level endorsement, the number of adaptive Phase II/III trials in rare cancers needs to be improved, with better understanding of their value for clinical decisions in daily practice. This paper describes approaches to trial design in rare cancers, which has been supplemented by a search...

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Detalles Bibliográficos
Autores principales: Krendyukov, Andriy, Singhvi, Sanjay, Zabransky, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982798/
https://www.ncbi.nlm.nih.gov/pubmed/33763370
http://dx.doi.org/10.3389/fonc.2021.636561