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Targeted RNA-Based Oxford Nanopore Sequencing for Typing 12 Classical HLA Genes

Identification of human leukocyte antigen (HLA) alleles from next-generation sequencing (NGS) data is challenging because of the high polymorphism and mosaic nature of HLA genes. Owing to the complex nature of HLA genes and consequent challenges in allele assignment, Oxford Nanopore Technologies’ (O...

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Detalles Bibliográficos
Autores principales: Johansson, Tiira, Koskela, Satu, Yohannes, Dawit A., Partanen, Jukka, Saavalainen, Päivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982845/
https://www.ncbi.nlm.nih.gov/pubmed/33763116
http://dx.doi.org/10.3389/fgene.2021.635601