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Targeted RNA-Based Oxford Nanopore Sequencing for Typing 12 Classical HLA Genes
Identification of human leukocyte antigen (HLA) alleles from next-generation sequencing (NGS) data is challenging because of the high polymorphism and mosaic nature of HLA genes. Owing to the complex nature of HLA genes and consequent challenges in allele assignment, Oxford Nanopore Technologies’ (O...
Autores principales: | Johansson, Tiira, Koskela, Satu, Yohannes, Dawit A., Partanen, Jukka, Saavalainen, Päivi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982845/ https://www.ncbi.nlm.nih.gov/pubmed/33763116 http://dx.doi.org/10.3389/fgene.2021.635601 |
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