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Adrenergic Mechanisms of Audiogenic Seizure-Induced Death in a Mouse Model of SCN8A Encephalopathy

Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death amongst patients whose seizures are not adequately controlled by current therapies. Patients with SCN8A encephalopathy have an elevated risk for SUDEP. While transgenic mouse models have provided insight into the molecular mec...

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Detalles Bibliográficos
Autores principales: Wengert, Eric R., Wenker, Ian C., Wagner, Elizabeth L., Wagley, Pravin K., Gaykema, Ronald P., Shin, Jung-Bum, Patel, Manoj K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982890/
https://www.ncbi.nlm.nih.gov/pubmed/33762902
http://dx.doi.org/10.3389/fnins.2021.581048