N6-Methyladenosine Induced miR-34a-5p Promotes TNF-α-Induced Nucleus Pulposus Cell Senescence by Targeting SIRT1

Low back pain is tightly associated with intervertebral disc degeneration (IVDD) and aberrant nucleus pulposus (NP) is a critical cause. miRNAs N6-methyladenosine (m6A) modification accounts for the TNF-α-induced senescence of NP cells. The aim of this study was to investigate whether m6A modificati...

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Detalles Bibliográficos
Autores principales: Zhu, Hao, Sun, Bao, Zhu, Liang, Zou, Guoyou, Shen, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982913/
https://www.ncbi.nlm.nih.gov/pubmed/33763423
http://dx.doi.org/10.3389/fcell.2021.642437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982913/
https://www.ncbi.nlm.nih.gov/pubmed/33763423
http://dx.doi.org/10.3389/fcell.2021.642437

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