UGT1A1 rs4148323 A Allele is Associated With Increased 2-Hydroxy Atorvastatin Formation and Higher Death Risk in Chinese Patients With Coronary Artery Disease

It is widely accepted that genetic polymorphisms impact atorvastatin (ATV) metabolism, clinical efficacy, and adverse events. The objectives of this study were to identify novel genetic variants influencing ATV metabolism and outcomes in Chinese patients with coronary artery disease (CAD). A total o...

Descripción completa

Detalles Bibliográficos
Autores principales: Lei, He-Ping, Qin, Min, Cai, Li-Yun, Wu, Hong, Tang, Lan, Liu, Ju-E, Deng, Chun-Yu, Liu, Yi-Bin, Zhu, Qian, Li, Han-Ping, Hu, Wei, Yang, Min, Zhu, Yi-Zhun, Zhong, Shi-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982952/
https://www.ncbi.nlm.nih.gov/pubmed/33762934
http://dx.doi.org/10.3389/fphar.2021.586973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982952/
https://www.ncbi.nlm.nih.gov/pubmed/33762934
http://dx.doi.org/10.3389/fphar.2021.586973

Ejemplares similares