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Remote ischaemic preconditioning ameliorates anthracycline-induced cardiotoxicity and preserves mitochondrial integrity

AIMS: Anthracycline-induced cardiotoxicity (AIC) is a serious adverse effect among cancer patients. A central mechanism of AIC is irreversible mitochondrial damage. Despite major efforts, there are currently no effective therapies able to prevent AIC. METHODS AND RESULTS: Forty Large-White pigs were...

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Detalles Bibliográficos
Autores principales: Galán-Arriola, Carlos, Villena-Gutiérrez, Rocio, Higuero-Verdejo, María I, Díaz-Rengifo, Iván A, Pizarro, Gonzalo, López, Gonzalo J, de Molina-Iracheta, Antonio, Pérez-Martínez, Claudia, García, Rodrigo D, González-Calle, David, Lobo, Manuel, Sánchez, Pedro L, Oliver, Eduardo, Córdoba, Raúl, Fuster, Valentin, Sánchez-González, Javier, Ibanez, Borja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983009/
https://www.ncbi.nlm.nih.gov/pubmed/32597960
http://dx.doi.org/10.1093/cvr/cvaa181