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Inhibition of TLR4 signaling protects mice from sensory and motor dysfunction in an animal model of autoimmune peripheral neuropathy

BACKGROUND: While the etiology remains elusive, macrophages and T cells in peripheral nerves are considered as effector cells mediating autoimmune peripheral neuropathy (APN), such as Guillain-Barre syndrome. By recognizing both pathogen-associated molecular patterns (PAMPs) and damage-associated mo...

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Detalles Bibliográficos
Autores principales: Oladiran, Oladayo, Shi, Xiang Qun, Yang, Mu, Fournier, Sylvie, Zhang, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983271/
https://www.ncbi.nlm.nih.gov/pubmed/33752705
http://dx.doi.org/10.1186/s12974-021-02126-x