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Hedgehog signaling in endocrine and folliculo-stellate cells of the adult pituitary

Ubiquitous overactivation of Hedgehog signaling in adult pituitaries results in increased expression of proopiomelanocortin (Pomc), growth hormone (Gh) and prolactin (Prl), elevated adrenocorticotropic hormone (Acth) production and proliferation of Sox2(+) cells. Moreover, ACTH, GH and PRL-expressin...

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Detalles Bibliográficos
Autores principales: Botermann, Dominik Simon, Brandes, Nadine, Frommhold, Anke, Heß, Ina, Wolff, Alexander, Zibat, Arne, Hahn, Heidi, Buslei, Rolf, Uhmann, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983331/
https://www.ncbi.nlm.nih.gov/pubmed/33480359
http://dx.doi.org/10.1530/JOE-20-0388