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Hedgehog signaling in endocrine and folliculo-stellate cells of the adult pituitary
Ubiquitous overactivation of Hedgehog signaling in adult pituitaries results in increased expression of proopiomelanocortin (Pomc), growth hormone (Gh) and prolactin (Prl), elevated adrenocorticotropic hormone (Acth) production and proliferation of Sox2(+) cells. Moreover, ACTH, GH and PRL-expressin...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983331/ https://www.ncbi.nlm.nih.gov/pubmed/33480359 http://dx.doi.org/10.1530/JOE-20-0388 |