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RET mutated C-cells proliferate more rapidly than non-mutated neoplastic cells

A statistically significant higher prevalence of the RET p.Met918Thr somatic mutation, identified by direct sequencing, was previously reported in MTC > 2 cm than in smaller tumors. Aim of this study was to correlate the full RET and RAS mutation profile, identified by a Next Generation Sequencin...

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Detalles Bibliográficos
Autores principales: Romei, Cristina, Ramone, Teresa, Mulè, Chiara, Prete, Alessandro, Cappagli, Virginia, Lorusso, Loredana, Torregrossa, Liborio, Basolo, Fulvio, Ciampi, Raffaele, Elisei, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983519/
https://www.ncbi.nlm.nih.gov/pubmed/33475524
http://dx.doi.org/10.1530/EC-20-0589