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RET mutated C-cells proliferate more rapidly than non-mutated neoplastic cells
A statistically significant higher prevalence of the RET p.Met918Thr somatic mutation, identified by direct sequencing, was previously reported in MTC > 2 cm than in smaller tumors. Aim of this study was to correlate the full RET and RAS mutation profile, identified by a Next Generation Sequencin...
Autores principales: | Romei, Cristina, Ramone, Teresa, Mulè, Chiara, Prete, Alessandro, Cappagli, Virginia, Lorusso, Loredana, Torregrossa, Liborio, Basolo, Fulvio, Ciampi, Raffaele, Elisei, Rossella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983519/ https://www.ncbi.nlm.nih.gov/pubmed/33475524 http://dx.doi.org/10.1530/EC-20-0589 |
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