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MAPT haplotype–stratified GWAS reveals differential association for AD risk variants

INTRODUCTION: MAPT H1 haplotype is implicated as a risk factor for neurodegenerative diseases including Alzheimer's disease (AD). METHODS: Using Alzheimer's Disease Genetics Consortium (ADGC) genome‐wide association study (GWAS) data (n = 18,841), we conducted a MAPT H1/H2 haplotype–strati...

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Detalles Bibliográficos
Autores principales: Strickland, Samantha L., Reddy, Joseph S., Allen, Mariet, N'songo, Aurelie, Burgess, Jeremy D., Corda, Morgane M., Ballard, Travis, Wang, Xue, Carrasquillo, Minerva M., Biernacka, Joanna M., Jenkins, Gregory D., Mukherjee, Shubhabrata, Boehme, Kevin, Crane, Paul, Kauwe, John S., Ertekin‐Taner, Nilüfer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983911/
https://www.ncbi.nlm.nih.gov/pubmed/32400971
http://dx.doi.org/10.1002/alz.12099