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MAPT haplotype–stratified GWAS reveals differential association for AD risk variants
INTRODUCTION: MAPT H1 haplotype is implicated as a risk factor for neurodegenerative diseases including Alzheimer's disease (AD). METHODS: Using Alzheimer's Disease Genetics Consortium (ADGC) genome‐wide association study (GWAS) data (n = 18,841), we conducted a MAPT H1/H2 haplotype–strati...
Autores principales: | Strickland, Samantha L., Reddy, Joseph S., Allen, Mariet, N'songo, Aurelie, Burgess, Jeremy D., Corda, Morgane M., Ballard, Travis, Wang, Xue, Carrasquillo, Minerva M., Biernacka, Joanna M., Jenkins, Gregory D., Mukherjee, Shubhabrata, Boehme, Kevin, Crane, Paul, Kauwe, John S., Ertekin‐Taner, Nilüfer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983911/ https://www.ncbi.nlm.nih.gov/pubmed/32400971 http://dx.doi.org/10.1002/alz.12099 |
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