Cerebellar developmental deficits underlie neurodegenerative disorder spinocerebellar ataxia type 23

Spinocerebellar ataxia type 23 (SCA23) is a late‐onset neurodegenerative disorder characterized by slowly progressive gait and limb ataxia, for which there is no therapy available. It is caused by pathogenic variants in PDYN, which encodes prodynorphin (PDYN). PDYN is processed into the opioid pepti...

Descripción completa

Detalles Bibliográficos
Autores principales: Smeets, Cleo J.L.M., Ma, Kai Yu, Fisher, Simon E., Verbeek, Dineke S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983976/
https://www.ncbi.nlm.nih.gov/pubmed/33043513
http://dx.doi.org/10.1111/bpa.12905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983976/
https://www.ncbi.nlm.nih.gov/pubmed/33043513
http://dx.doi.org/10.1111/bpa.12905

Ejemplares similares