Impairing committed cholesterol biosynthesis in white matter astrocytes, but not grey matter astrocytes, enhances in vitro myelination

Remyelination is a regenerative process that is essential to recover saltatory conduction and to prevent neurodegeneration upon demyelination. The formation of new myelin involves the differentiation of oligodendrocyte progenitor cells (OPCs) toward oligodendrocytes and requires high amounts of chol...

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Detalles Bibliográficos
Autores principales: Werkman, Inge L., Kövilein, Janine, de Jonge, Jenny C., Baron, Wia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984098/
https://www.ncbi.nlm.nih.gov/pubmed/32602556
http://dx.doi.org/10.1111/jnc.15113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984098/
https://www.ncbi.nlm.nih.gov/pubmed/32602556
http://dx.doi.org/10.1111/jnc.15113

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