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Proenkephalin Decreases in Cerebrospinal Fluid with Symptom Progression of Huntington's Disease

OBJECTIVE: Identifying molecular changes that contribute to the onset and progression of Huntington's disease (HD) is of importance for the development and evaluation of potential therapies. METHODS: We conducted an unbiased mass‐spectrometry proteomic analysis on the cerebrospinal fluid of 12...

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Detalles Bibliográficos
Autores principales: Niemela, Valter, Landtblom, Anne‐Marie, Nyholm, Dag, Kneider, Maria, Constantinescu, Radu, Paucar, Martin, Svenningsson, Per, Abujrais, Sandy, Burman, Joachim, Shevchenko, Ganna, Bergquist, Jonas, Sundblom, Jimmy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984171/
https://www.ncbi.nlm.nih.gov/pubmed/33247616
http://dx.doi.org/10.1002/mds.28391