Modulation of cortical slow oscillatory rhythm by GABA(B) receptors: an in vitro experimental and computational study

KEY POINTS: We confirm that GABA(B) receptors (GABA(B)‐Rs) are involved in the termination of Up‐states; their blockade consistently elongates Up‐states. GABA(B)‐Rs also modulate Down‐states and the oscillatory cycle, thus having an impact on slow oscillation rhythm and its regularity. The most freq...

Descripción completa

Detalles Bibliográficos
Autores principales: Perez‐Zabalza, Maria, Reig, Ramon, Manrique, Jesus, Jercog, Daniel, Winograd, Milena, Parga, Nestor, Sanchez‐Vives, Maria V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984206/
https://www.ncbi.nlm.nih.gov/pubmed/32406934
http://dx.doi.org/10.1113/JP279476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984206/
https://www.ncbi.nlm.nih.gov/pubmed/32406934
http://dx.doi.org/10.1113/JP279476

Ejemplares similares