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The secondary‐structured DNA‐binding activity of Dna2 endonuclease/helicase is critical to cell growth under replication stress

Dna2 can efficiently process 5′ flaps containing DNA secondary structure using coordinated action of the three biochemical activities: the N‐terminally encoded DNA‐binding activity and the C‐terminally encoded endonuclease and helicase activities. In this study, we investigated the cross talk among...

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Detalles Bibliográficos
Autores principales: Park, Soyeong, Karatayeva, Nargis, Demin, Annie Albert, Munashingha, Palinda Ruvan, Seo, Yeon‐Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984218/
https://www.ncbi.nlm.nih.gov/pubmed/32638513
http://dx.doi.org/10.1111/febs.15475