Structure‐based design of peptides that trigger Streptococcus pneumoniae cell death

Toxin–antitoxin (TA) systems regulate key cellular functions in bacteria. Here, we report a unique structure of the Streptococcus pneumoniae HigBA system and a novel antimicrobial agent that activates HigB toxin, which results in mRNA degradation as an antibacterial strategy. In this study, protein...

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Detalles Bibliográficos
Autores principales: Kang, Sung‐Min, Jin, Chenglong, Kim, Do‐Hee, Park, Sung Jean, Han, Sang‐Woo, Lee, Bong‐Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984235/
https://www.ncbi.nlm.nih.gov/pubmed/32770723
http://dx.doi.org/10.1111/febs.15514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984235/
https://www.ncbi.nlm.nih.gov/pubmed/32770723
http://dx.doi.org/10.1111/febs.15514

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