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Clusterin regulates macrophage expansion, polarization and phagocytic activity in response to inflammation in the kidneys

Clusterin (CLU) is a multifunctional protein localized extracellularly and intracellularly. Although CLU‐knockout (KO) mice are more susceptible to renal ischemia‐reperfusion injury (IRI), the mechanisms underlying the actions of CLU in IRI are not fully understood. Macrophages are key regulators of...

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Detalles Bibliográficos
Autores principales: Weng, Xiaodong, Zhao, Haimei, Guan, Qiunong, Shi, Ganggang, Feng, Shijian, Gleave, Martin E, Nguan, Christopher CY, Du, Caigan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984284/
https://www.ncbi.nlm.nih.gov/pubmed/32935392
http://dx.doi.org/10.1111/imcb.12405