Structural Insights into the Interaction of Heme with Protein Tyrosine Kinase JAK2

Janus kinase 2 (JAK2) is the most important signal‐transducing tyrosine kinase in erythropoietic precursor cells. Its malfunction drives several myeloproliferative disorders. Heme is a small metal‐ion‐carrying molecule that is incorporated into hemoglobin in erythroid precursor cells to transport ox...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmalohr, Benjamin Franz, Mustafa, Al‐Hassan M., Krämer, Oliver H., Imhof, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984354/
https://www.ncbi.nlm.nih.gov/pubmed/33103835
http://dx.doi.org/10.1002/cbic.202000730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984354/
https://www.ncbi.nlm.nih.gov/pubmed/33103835
http://dx.doi.org/10.1002/cbic.202000730

Ejemplares similares