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The APOE ε4 exerts differential effects on familial and other subtypes of Alzheimer's disease

INTRODUCTION: The genetic risk effects of apolipoprotein E (APOE) on familial Alzheimer's disease (FAD) with or without gene mutations, sporadic AD (SAD), and normal controls (NC) remain unclear in the Chinese population. METHODS: In total, 15 119 subjects, including 311 FAD patients without PS...

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Detalles Bibliográficos
Autores principales: Jia, Longfei, Xu, Hui, Chen, Shuoqi, Wang, Xiu, Yang, Jianwei, Gong, Min, Wei, Cuibai, Tang, Yi, Qu, Qiumin, Chu, Lan, Shen, Lu, Zhou, Chunkui, Wang, Qi, Zhao, Tan, Zhou, Aihong, Li, Ying, Li, Fangyu, Li, Yan, Jin, Hongmei, Qin, Qi, Jiao, Haishan, Zhang, Heng, Lyu, Diyang, Shi, Yuqing, Song, Yang, Jia, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984370/
https://www.ncbi.nlm.nih.gov/pubmed/32881347
http://dx.doi.org/10.1002/alz.12153