Safety, Tolerability, and Dose Proportionality of a Novel Transdermal Fentanyl Matrix Patch and Bioequivalence With a Matrix Fentanyl Patch: Two Phase 1 Single‐Center Open‐Label, Randomized Crossover Studies in Healthy Japanese Volunteers

Two open‐label, single‐dose, randomized crossover studies were conducted in healthy Japanesemen to (1) assess dose proportionality of 5 doses (1.38, 2.75, 5.5, 8.25, and 11.0 mg) of Lafenta, a novel matrix‐type transdermal fentanyl patch with a rate‐controlling membrane; and (2) compare patch bioequ...

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Detalles Bibliográficos
Autores principales: Lorch, Ulrike, Pierscionek, Tomasz, Freier, Anne, Spencer, Christopher S., Täubel, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984375/
https://www.ncbi.nlm.nih.gov/pubmed/32748570
http://dx.doi.org/10.1002/cpdd.846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984375/
https://www.ncbi.nlm.nih.gov/pubmed/32748570
http://dx.doi.org/10.1002/cpdd.846

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