Proteomics‐Informed Prediction of Rosuvastatin Plasma Profiles in Patients With a Wide Range of Body Weight

Rosuvastatin is a frequently used probe to study transporter‐mediated hepatic uptake. Pharmacokinetic models have therefore been developed to predict transporter impact on rosuvastatin disposition in vivo. However, the interindividual differences in transporter concentrations were not considered in...

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Detalles Bibliográficos
Autores principales: Wegler, Christine, Prieto Garcia, Luna, Klinting, Signe, Robertsen, Ida, Wiśniewski, Jacek R., Hjelmesæth, Jøran, Åsberg, Anders, Jansson‐Löfmark, Rasmus, Andersson, Tommy B., Artursson, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984432/
https://www.ncbi.nlm.nih.gov/pubmed/32970864
http://dx.doi.org/10.1002/cpt.2056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984432/
https://www.ncbi.nlm.nih.gov/pubmed/32970864
http://dx.doi.org/10.1002/cpt.2056

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