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Proteomics‐Informed Prediction of Rosuvastatin Plasma Profiles in Patients With a Wide Range of Body Weight
Rosuvastatin is a frequently used probe to study transporter‐mediated hepatic uptake. Pharmacokinetic models have therefore been developed to predict transporter impact on rosuvastatin disposition in vivo. However, the interindividual differences in transporter concentrations were not considered in...
Autores principales: | Wegler, Christine, Prieto Garcia, Luna, Klinting, Signe, Robertsen, Ida, Wiśniewski, Jacek R., Hjelmesæth, Jøran, Åsberg, Anders, Jansson‐Löfmark, Rasmus, Andersson, Tommy B., Artursson, Per |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984432/ https://www.ncbi.nlm.nih.gov/pubmed/32970864 http://dx.doi.org/10.1002/cpt.2056 |
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