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Towards Dissecting the Mechanism of Protein Phosphatase‐1 Inhibition by Its C‐Terminal Phosphorylation

Phosphoprotein phosphatase‐1 (PP1) is a key player in the regulation of phospho‐serine (pSer) and phospho‐threonine (pThr) dephosphorylation and is involved in a large fraction of cellular signaling pathways. Aberrant activity of PP1 has been linked to many diseases, including cancer and heart failu...

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Detalles Bibliográficos
Autores principales: Salvi, Francesca, Hoermann, Bernhard, del Pino García, Javier, Fontanillo, Miriam, Derua, Rita, Beullens, Monique, Bollen, Mathieu, Barabas, Orsolya, Köhn, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984433/
https://www.ncbi.nlm.nih.gov/pubmed/33085143
http://dx.doi.org/10.1002/cbic.202000669