Caenorhabditis elegans F-Box Protein Promotes Axon Regeneration by Inducing Degradation of the Mad Transcription Factor

In Caenorhabditis elegans, axon regeneration is activated by a signaling cascade through the receptor tyrosine kinase (RTK) SVH-2. Axonal injury induces svh-2 gene expression by degradation of the Mad-like transcription factor MDL-1. In this study, we identify the svh-24/sdz-33 gene encoding a prote...

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Detalles Bibliográficos
Autores principales: Shimizu, Tatsuhiro, Pastuhov, Strahil I., Hanafusa, Hiroshi, Sakai, Yoshiki, Todoroki, Yasuko, Hisamoto, Naoki, Matsumoto, Kunihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984584/
https://www.ncbi.nlm.nih.gov/pubmed/33514673
http://dx.doi.org/10.1523/JNEUROSCI.1024-20.2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984584/
https://www.ncbi.nlm.nih.gov/pubmed/33514673
http://dx.doi.org/10.1523/JNEUROSCI.1024-20.2021

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