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Combinatorial mathematical modelling approaches to interrogate rear retraction dynamics in 3D cell migration

Cell migration in 3D microenvironments is a complex process which depends on the coordinated activity of leading edge protrusive force and rear retraction in a push-pull mechanism. While the potentiation of protrusions has been widely studied, the precise signalling and mechanical events that lead t...

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Detalles Bibliográficos
Autores principales: Hetmanski, Joseph H. R., Jones, Matthew C., Chunara, Fatima, Schwartz, Jean-Marc, Caswell, Patrick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984637/
https://www.ncbi.nlm.nih.gov/pubmed/33690598
http://dx.doi.org/10.1371/journal.pcbi.1008213