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Ex Vivo Models to Decipher the Molecular Mechanisms of Genetic Notch Cardiovascular Disorders

Notch is an evolutionary, conserved, cell–cell signaling pathway that is central to several biological processes, from tissue morphogenesis to homeostasis. It is therefore not surprising that several genetic mutations of Notch components cause inherited human diseases, especially cardiovascular diso...

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Detalles Bibliográficos
Autores principales: Ristori, Tommaso, Sjöqvist, Marika, Sahlgren, Cecilia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984653/
https://www.ncbi.nlm.nih.gov/pubmed/33403934
http://dx.doi.org/10.1089/ten.tec.2020.0327