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A high-content AlphaScreen™ identifies E6-specific small molecule inhibitors as potential therapeutics for HPV(+) head and neck squamous cell carcinomas
The incidence of human papillomavirus-positive head and neck squamous cell carcinoma (HPV(+)-HNSCC) has increased dramatically over the past decades due to an increase in infection of the oral mucosa by HPV. The etiology of HPV(+)-HNSCC is linked to expression of the HPV oncoprotein, E6, which influ...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984827/ https://www.ncbi.nlm.nih.gov/pubmed/33796223 http://dx.doi.org/10.18632/oncotarget.27908 |