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Morphine coordinates SST and PV interneurons in the prelimbic cortex to disinhibit pyramidal neurons and enhance reward
Opioids, such as morphine, are clinic analgesics which induce euphoria. Morphine exposure modifies the excitability and functional interactions between neurons, while the underlying cellular and molecular mechanisms, especially how morphine assembles heterogeneous interneurons (INs) in prelimbic cor...
Autores principales: | Jiang, Changyou, Wang, Xueying, Le, Qiumin, Liu, Peipei, Liu, Cao, Wang, Zhilin, He, Guanhong, Zheng, Ping, Wang, Feifei, Ma, Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985023/ https://www.ncbi.nlm.nih.gov/pubmed/31413370 http://dx.doi.org/10.1038/s41380-019-0480-7 |
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