Fusion partners of NTRK3 affect subcellular localization of the fusion kinase and cytomorphology of melanocytes

A subset of Spitz tumors harbor fusions of NTRK3 with ETV6, MYO5A, and MYH9. We evaluated a series of 22 melanocytic tumors in which an NTRK3 fusion was identified as part of the diagnostic workup. Tumors in which NTRK3 was fused to ETV6 occurred in younger patients, were predominantly composed of e...

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Detalles Bibliográficos
Autores principales: de la Fouchardière, Arnaud, Tee, Meng Kian, Peternel, Sandra, Valdebran, Manuel, Pissaloux, Daniel, Tirode, Franck, Busam, Klaus J., LeBoit, Philip E., McCalmont, Timothy H., Bastian, Boris C., Yeh, Iwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985048/
https://www.ncbi.nlm.nih.gov/pubmed/32968185
http://dx.doi.org/10.1038/s41379-020-00678-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985048/
https://www.ncbi.nlm.nih.gov/pubmed/32968185
http://dx.doi.org/10.1038/s41379-020-00678-6

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