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Fusion partners of NTRK3 affect subcellular localization of the fusion kinase and cytomorphology of melanocytes
A subset of Spitz tumors harbor fusions of NTRK3 with ETV6, MYO5A, and MYH9. We evaluated a series of 22 melanocytic tumors in which an NTRK3 fusion was identified as part of the diagnostic workup. Tumors in which NTRK3 was fused to ETV6 occurred in younger patients, were predominantly composed of e...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985048/ https://www.ncbi.nlm.nih.gov/pubmed/32968185 http://dx.doi.org/10.1038/s41379-020-00678-6 |