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Connexin 43 phosphorylation by casein kinase 1 is essential for the cardioprotection by ischemic preconditioning

Myocardial connexin 43 (Cx43) forms gap junctions and hemichannels, and is also present within subsarcolemmal mitochondria. The protein is phosphorylated by several kinases including mitogen-activated protein kinase (MAPK), protein kinase C (PKC), and casein kinase 1 (CK1). A reduction in Cx43 conte...

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Detalles Bibliográficos
Autores principales: Hirschhäuser, Christine, Lissoni, Alessio, Görge, Philipp Maximilian, Lampe, Paul D., Heger, Jacqueline, Schlüter, Klaus-Dieter, Leybaert, Luc, Schulz, Rainer, Boengler, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985055/
https://www.ncbi.nlm.nih.gov/pubmed/33751227
http://dx.doi.org/10.1007/s00395-021-00861-z