Cargando…

Connexin 43 phosphorylation by casein kinase 1 is essential for the cardioprotection by ischemic preconditioning

Myocardial connexin 43 (Cx43) forms gap junctions and hemichannels, and is also present within subsarcolemmal mitochondria. The protein is phosphorylated by several kinases including mitogen-activated protein kinase (MAPK), protein kinase C (PKC), and casein kinase 1 (CK1). A reduction in Cx43 conte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hirschhäuser, Christine, Lissoni, Alessio, Görge, Philipp Maximilian, Lampe, Paul D., Heger, Jacqueline, Schlüter, Klaus-Dieter, Leybaert, Luc, Schulz, Rainer, Boengler, Kerstin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Original Contribution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985055/ https://www.ncbi.nlm.nih.gov/pubmed/33751227 http://dx.doi.org/10.1007/s00395-021-00861-z

Ejemplares similares

S-nitrosation of mitochondrial connexin 43 regulates mitochondrial function
por: Soetkamp, Daniel, et al.
Publicado: (2014)

Connexin 43 impacts on mitochondrial potassium uptake
por: Boengler, Kerstin, et al.
Publicado: (2013)

Connexin 43 in Mitochondria: What Do We Really Know About Its Function?
por: Boengler, Kerstin, et al.
Publicado: (2022)

Cardioprotection in right heart failure
por: Boengler, Kerstin, et al.
Publicado: (2020)

Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke
por: Freitas-Andrade, Moises, et al.
Publicado: (2019)

Lack of Contribution of p66shc and Its Mitochondrial Translocation to Ischemia-Reperfusion Injury and Cardioprotection by Ischemic Preconditioning
por: Boengler, Kerstin, et al.
Publicado: (2017)

Connexin hemichannels as candidate targets for cardioprotective and anti-arrhythmic treatments
por: Leybaert, Luc, et al.
Publicado: (2023)

Remote ischemic preconditioning preserves Connexin 43 phosphorylation in the rat heart in vivo
por: Brandenburger, Timo, et al.
Publicado: (2014)

Canonical and Non-Canonical Roles of Connexin43 in Cardioprotection
por: Rusiecka, Olga M., et al.
Publicado: (2020)

Involvement of Endothelin 1 in Remote Preconditioning-Induced Cardioprotection through connexin 43 and Akt/GSK-3β Signaling Pathway
por: Zhang, Min, et al.
Publicado: (2018)

Astrocytic Connexin43 Channels as Candidate Targets in Epilepsy Treatment
por: Walrave, Laura, et al.
Publicado: (2020)

Connexin 43 Phosphorylation: Implications in Multiple Diseases
por: Zhang, Meng, et al.
Publicado: (2023)

Non-responsiveness to cardioprotection by ischaemic preconditioning in Ossabaw minipigs with genetic predisposition to, but without the phenotype of the metabolic syndrome
por: Kleinbongard, Petra, et al.
Publicado: (2022)

Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion
por: Boengler, Kerstin, et al.
Publicado: (2010)

Mitochondrial connexin 43 impacts on respiratory complex I activity and mitochondrial oxygen consumption
por: Boengler, Kerstin, et al.
Publicado: (2012)

Importance of Cx43 for Right Ventricular Function
por: Boengler, Kerstin, et al.
Publicado: (2021)

Phosphorylation of Connexin43 on Serine368 by Protein Kinase C Regulates Gap Junctional Communication
por: Lampe, Paul D., et al.
Publicado: (2000)

The Ambivalence of Connexin43 Gap Peptides in Cardioprotection of the Isolated Heart against Ischemic Injury
por: Falck, Aleksander Tank, et al.
Publicado: (2022)

Effects of ischemic preconditioning on ischemia/reperfusion-induced arrhythmias by upregulatation of connexin 43 expression
por: Chen, Zhenguang, et al.
Publicado: (2011)

Connexin43 Hemichannel-Mediated Regulation of Connexin43
por: Li, Kai, et al.
Publicado: (2013)

Interaction between Connexin 43 and nitric oxide synthase in mice heart mitochondria
por: Kirca, Mücella, et al.
Publicado: (2015)

AMPKα1 deletion in myofibroblasts exacerbates post-myocardial infarction fibrosis by a connexin 43 mechanism
por: Dufeys, Cécile, et al.
Publicado: (2021)

LRP6-mediated phosphorylation of connexin43 in myocardial infarction
por: Zhang, Xu-min, et al.
Publicado: (2023)

Impact of Anesthetics on Cardioprotection Induced by Pharmacological Preconditioning
por: Bunte, Sebastian, et al.
Publicado: (2019)

Cx43 Hemichannel and Panx1 Channel Modulation by Gap19 and (10)Panx1 Peptides
por: Lissoni, Alessio, et al.
Publicado: (2023)

Glycated serum albumin decreases connexin 43 phosphorylation in the corpus cavernosum
por: Huang, Yanping, et al.
Publicado: (2022)

Role of Connexin 43 phosphorylation on Serine-368 by PKC in cardiac function and disease
por: Pun, Renju, et al.
Publicado: (2023)

Nitric oxide, PKC-ε, and connexin43 are crucial for ischemic preconditioning-induced chemical gap junction uncoupling
por: Rong, Bing, et al.
Publicado: (2016)

Connexin 26 and Connexin 43 in Canine Mammary Carcinoma
por: Luu, Savannah, et al.
Publicado: (2019)

Lack of Contribution of p66shc to Pressure Overload-Induced Right Heart Hypertrophy
por: Hirschhäuser, Christine, et al.
Publicado: (2020)

Inhibition of Connexin43 Hemichannels Impairs Spatial Short-Term Memory without Affecting Spatial Working Memory
por: Walrave, Laura, et al.
Publicado: (2016)

Connexin43 Hemichannel Targeting With TAT-Gap19 Alleviates Radiation-Induced Endothelial Cell Damage
por: Ramadan, Raghda, et al.
Publicado: (2020)

Function of Connexin-43 in Macrophages
por: Rodjakovic, Daniel, et al.
Publicado: (2021)

Internal translation of Gja1 (Connexin43) to produce GJA1-20k: Implications for arrhythmia and ischemic-preconditioning
por: Whisenant, Claire C., et al.
Publicado: (2022)

Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaques
Publicado: (1991)

Connexin43 phosphorylation by PKC and MAPK signals VEGF-mediated gap junction internalization
por: Nimlamool, Wutigri, et al.
Publicado: (2015)

Involvement of PKCε in FSH-induced connexin43 phosphorylation and oocyte maturation in mouse
por: Cai, Han, et al.
Publicado: (2018)

Autophagy Induced by Ischemic Preconditioning is Essential for Cardioprotection
por: Huang, Chengqun, et al.
Publicado: (2010)

Ser364 of connexin43 and the upregulation of gap junction assembly by cAMP
por: TenBroek, Erica M., et al.
Publicado: (2001)

Protein kinase C spatially and temporally regulates gap junctional communication during human wound repair via phosphorylation of connexin43 on serine368
por: Richards, Theresa S., et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_59kguc3ercvkum178ii9e82dr2