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Phenotypic and Functional Analyses Guiding Combination Immune Checkpoint Immunotherapeutic Strategies in HTLV-1 Infection

Human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) develops in 1–5% of HTLV-1-infected individuals. Previous studies by us and others have shown that the expression of negative immune checkpoint receptors (NCRs) is significantly increased on...

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Detalles Bibliográficos
Autores principales: Clements, Danielle M., Crumley, Brenndan, Chew, Glen M., Davis, Elijah, Bruhn, Roberta, Murphy, Edward L., Ndhlovu, Lishomwa C., Jain, Pooja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985073/
https://www.ncbi.nlm.nih.gov/pubmed/33767694
http://dx.doi.org/10.3389/fimmu.2021.608890