Cargando…
Potential Impact of DPYD Variation on Fluoropyrimidine Drug Response in sub-Saharan African Populations
Cancer is a critical health burden in Africa, and mortality rates are rising rapidly. Treatments are expensive and often cause adverse drug reactions (ADRs). Fluoropyrimidine treatments can lead to severe toxicity events which have been linked to variants within the dihydropyrimidine dehydrogenase (...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985174/ https://www.ncbi.nlm.nih.gov/pubmed/33767731 http://dx.doi.org/10.3389/fgene.2021.626954 |