Allele-specific expression: applications in cancer and technical considerations

Allele-specific gene expression can influence disease traits. Non-coding germline genetic variants that alter regulatory elements can cause allele-specific gene expression and contribute to cancer susceptibility. In tumors, both somatic copy number alterations and somatic single nucleotide variants...

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Detalles Bibliográficos
Autores principales: Robles-Espinoza, Carla Daniela, Mohammadi, Pejman, Bonilla, Ximena, Gutierrez-Arcelus, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985293/
https://www.ncbi.nlm.nih.gov/pubmed/33383480
http://dx.doi.org/10.1016/j.gde.2020.10.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985293/
https://www.ncbi.nlm.nih.gov/pubmed/33383480
http://dx.doi.org/10.1016/j.gde.2020.10.007

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