Comparisons of Polyexposure, Polygenic, and Clinical Risk Scores in Risk Prediction of Type 2 Diabetes

OBJECTIVE: To establish a polyexposure score (PXS) for type 2 diabetes (T2D) incorporating 12 nongenetic exposures and examine whether a PXS and/or a polygenic risk score (PGS) improves diabetes prediction beyond traditional clinical risk factors. RESEARCH DESIGN AND METHODS: We identified 356,621 u...

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Detalles Bibliográficos
Autores principales: He, Yixuan, Lakhani, Chirag M., Rasooly, Danielle, Manrai, Arjun K., Tzoulaki, Ioanna, Patel, Chirag J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Epidemiology/Health Services Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985424/
https://www.ncbi.nlm.nih.gov/pubmed/33563654
http://dx.doi.org/10.2337/dc20-2049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985424/
https://www.ncbi.nlm.nih.gov/pubmed/33563654
http://dx.doi.org/10.2337/dc20-2049

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