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A homogeneous split-luciferase assay for rapid and sensitive detection of anti-SARS CoV-2 antibodies

Better diagnostic tools are needed to combat the ongoing COVID-19 pandemic. Here, to meet this urgent demand, we report a homogeneous immunoassay to detect IgG antibodies against SARS-CoV-2. This serological assay, called SATiN, is based on a tri-part Nanoluciferase (tNLuc) approach, in which the sp...

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Detalles Bibliográficos
Autores principales: Yao, Zhong, Drecun, Luka, Aboualizadeh, Farzaneh, Kim, Sun Jin, Li, Zhijie, Wood, Heidi, Valcourt, Emelissa J., Manguiat, Kathy, Plenderleith, Simon, Yip, Lily, Li, Xinliu, Zhong, Zoe, Yue, Feng Yun, Closas, Tatiana, Snider, Jamie, Tomic, Jelena, Drews, Steven J., Drebot, Michael A., McGeer, Allison, Ostrowski, Mario, Mubareka, Samira, Rini, James M., Owen, Shawn, Stagljar, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985487/
https://www.ncbi.nlm.nih.gov/pubmed/33753733
http://dx.doi.org/10.1038/s41467-021-22102-6