Cargando…

Non-canonical role of wild-type SEC23B in the cellular stress response pathway

While germline recessive loss-of-function mutations in SEC23B in humans cause a rare form of anaemia, heterozygous change-of-function mutations result in increased predisposition to cancer. SEC23B encodes SEC23 homologue B, a component of coat protein complex II (COPII), which canonically transports...

Descripción completa

Detalles Bibliográficos
Autores principales: Yehia, Lamis, Liu, Darren, Fu, Shuai, Iyer, Pranav, Eng, Charis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985502/
https://www.ncbi.nlm.nih.gov/pubmed/33753724
http://dx.doi.org/10.1038/s41419-021-03589-9