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Optimized Detection of Acute MHV68 Infection With a Reporter System Identifies Large Peritoneal Macrophages as a Dominant Target of Primary Infection

Investigating the dynamics of virus-host interactions in vivo remains an important challenge, often limited by the ability to directly identify virally infected cells. Here, we utilize a beta-lactamase activated fluorescent substrate to identify primary targets of murine gammaherpesvirus 68 (MHV68)...

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Detalles Bibliográficos
Autores principales: Riggs, Julianne B., Medina, Eva M., Perrenoud, Loni J., Bonilla, Diana L., Clambey, Eric T., van Dyk, Linda F., Berg, Leslie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985543/
https://www.ncbi.nlm.nih.gov/pubmed/33767688
http://dx.doi.org/10.3389/fmicb.2021.656979