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N-Oleoylglycine and N-Oleoylalanine Do Not Modify Tolerance to Nociception, Hyperthermia, and Suppression of Activity Produced by Morphine

The endogenous amide N-Oleoylglycine (OlGly) and its analog N-Oleoylalanine (OlAla), have been shown to interfere with the affective and somatic responses to acute naloxone-precipitated MWD in male rats. Here we evaluated the potential of a single dose (5 mg/kg, ip) which alleviates withdrawal of th...

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Detalles Bibliográficos
Autores principales: Rock, Erin M., Limebeer, Cheryl L., Sullivan, Megan T., DeVuono, Marieka V., Lichtman, Aron H., Di Marzo, Vincenzo, Mechoulam, Raphael, Parker, Linda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985545/
https://www.ncbi.nlm.nih.gov/pubmed/33767617
http://dx.doi.org/10.3389/fnsyn.2021.620145