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Host transcriptional response to TB preventive therapy differentiates two sub-groups of IGRA-positive individuals

We hypothesised that individuals with immunological sensitisation to Mycobacterium tuberculosis (Mtb), conventionally regarded as evidence of latent tuberculosis infection (LTBI), would demonstrate binary responses to preventive therapy (PT), reflecting the differential immunological consequences of...

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Detalles Bibliográficos
Autores principales: Broderick, Claire, Cliff, Jacqueline M., Lee, Ji-Sook, Kaforou, Myrsini, Moore, David AJ.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Churchill Livingstone 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985621/
https://www.ncbi.nlm.nih.gov/pubmed/33524936
http://dx.doi.org/10.1016/j.tube.2020.102033