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Host transcriptional response to TB preventive therapy differentiates two sub-groups of IGRA-positive individuals
We hypothesised that individuals with immunological sensitisation to Mycobacterium tuberculosis (Mtb), conventionally regarded as evidence of latent tuberculosis infection (LTBI), would demonstrate binary responses to preventive therapy (PT), reflecting the differential immunological consequences of...
Autores principales: | Broderick, Claire, Cliff, Jacqueline M., Lee, Ji-Sook, Kaforou, Myrsini, Moore, David AJ. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Churchill Livingstone
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985621/ https://www.ncbi.nlm.nih.gov/pubmed/33524936 http://dx.doi.org/10.1016/j.tube.2020.102033 |
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