Cargando…
Response adaptive designs for Phase II trials with binary endpoint based on context-dependent information measures()
In many rare disease Phase II clinical trials, two objectives are of interest to an investigator: maximising the statistical power and maximising the number of patients responding to the treatment. These two objectives are competing, therefore, clinical trial designs offering a balance between them...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier B.V
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985674/ https://www.ncbi.nlm.nih.gov/pubmed/34083846 http://dx.doi.org/10.1016/j.csda.2021.107187 |