Comparative analysis of mutational hotspots in the spike protein of SARS-CoV-2 isolates from different geographic origins

The spike (S) protein mutations of SARS-CoV-2 are of major concern in terms of viral transmission and pathogenesis. Hence, we developed a PCR-based method to rapidly detect the 6 mutational hotspots (H49Y, G476S, V483A, H519Q, A520S, and D614G) in the S protein and applied this method to analyze the...

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Detalles Bibliográficos
Autores principales: Lee, Sanghoo, Lee, Mi-Kyeong, Na, Hyeongkyun, Ahn, Jinwoo, Hong, Gayeon, Lee, Youngkee, Park, Jimyeong, Kim, Yejin, Kim, Yun-Tae, Kim, Chang-Ki, Lim, Hwan-Sub, Lee, Kyoung-Ryul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985685/
https://www.ncbi.nlm.nih.gov/pubmed/33778182
http://dx.doi.org/10.1016/j.genrep.2021.101100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985685/
https://www.ncbi.nlm.nih.gov/pubmed/33778182
http://dx.doi.org/10.1016/j.genrep.2021.101100

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