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Specific epitopes form extensive hydrogen-bonding networks to ensure efficient antibody binding of SARS-CoV-2: Implications for advanced antibody design

Neutralizing antibody targeting to the SARS-CoV-2 could provide powerful therapies. A neutralizing antibody CC12.1 which was found in SARS-CoV-2 patient samples provides potential protection from disease. The aim of molecular dynamics simulations is to identify key epitopes that are crucial to the a...

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Detalles Bibliográficos
Autores principales: Wang, Daojiong, Ge, Yushu, Zhong, Bin, Liu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985686/
https://www.ncbi.nlm.nih.gov/pubmed/33777333
http://dx.doi.org/10.1016/j.csbj.2021.03.021