A Potential Mechanism Underlying the Therapeutic Effects of Progesterone and Allopregnanolone on Ketamine-Induced Cognitive Deficits

Ketamine exposure can model cognitive deficits associated with schizophrenia. Progesterone (PROG) and its active metabolite allopregnanolone (ALLO) have neuroprotective effects and the pathway involving progesterone receptor membrane component 1 (PGRMC1), epidermal growth factor receptor (EGFR), glu...

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Detalles Bibliográficos
Autores principales: Cao, Ting, Tang, MiMi, Jiang, Pei, Zhang, BiKui, Wu, XiangXin, Chen, Qian, Zeng, CuiRong, Li, NaNa, Zhang, ShuangYang, Cai, HuaLin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985688/
https://www.ncbi.nlm.nih.gov/pubmed/33767621
http://dx.doi.org/10.3389/fphar.2021.612083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985688/
https://www.ncbi.nlm.nih.gov/pubmed/33767621
http://dx.doi.org/10.3389/fphar.2021.612083

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